Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well performed OECD study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report Date:
2014

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
no
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
purity: 97.6 %

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
1.75
Temp.:
23 °C
pH:
> 7 - < 7.3
Details on results:
Results in detail:

determ. no. stock solution water test substance conc test substance conc.
[ml] [ml] in n-octanol phase in water phase Log Pow
[mg / L] [mg / L]

A1 5 10 6.4 0.10 1.80
A2 5 10 6.8 0.12 1.76
B1 10 10 6.6 0.13 1.70
B2 10 10 6.6 0.13 1.71
C1 20 10 6.8 0.11 1.79
C2 20 10 6.8 0.13 1.73
mean 1.75

Recovery rate of test substance: 94 - 101 %


Applicant's summary and conclusion

Conclusions:
Log Pow is 1.75 at 23 °C
Executive summary:

The partition coefficient n-octanol water of the substance was determined according OECD guideline 107. The Log Pow was found to be 1.75 at 23°C.