Registration Dossier
Registration Dossier
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EC number: 226-166-6 | CAS number: 5308-25-8
Endpoint summary
Administrative data
Description of key information
With high probability, 1-ethylpiperazine (CAS 5308-25-8) is considered to be acutely not harmful to aquatic organisms.
Additional information
Short-term toxicity to fish
With high probability, the substance is acutely not harmful to fish.
96-h LC50 = 316 mg/L (Leuciscus idus, DIN 38412, part 15, nominal, not pH-adjusted, BASF AG, 1990, rep. no.: 10F0950/885185).
Short-term toxicity to aquatic invertebrates:
With high probability the substance is acutely not harmful to aquatic invertebrates.
48-h EC50 = 199.3 mg/L (Daphnia magna, EU Method C.2, nominal, not pH-adjusted, BASF AG, 1988, rep.no.: 1/0002/2/88-0002/88).
Growth inhibition to aquatic algae:
With high probability acutely not harmful to algae.
The assessment is based on a read-across approach to a structurally similar substance: 1-methylpiperazine (CAS 109-01-3):
72 -h ErC50 > 352 mg/L, 72 -h ErC10 > 352 mg/L (OECD 201, nominal, analytically verified, pH-adjusted, BASF SE, 2013, rep. no.: 110907AG).
Toxicity to microorganisms:
The substance is not anticipated to inhibit the degradation activity of activated sludge when introduced in appropriately low concentrations.
1) 30 -min EC20 > 1000 mg/L. (domestic activated sludge, OECD 209, nominal, BASF AG, 1990, rep. no.: 01.0387/88)
2) 17-h EC10 = 141.4 mg/L (Pseudomonas putida, DIN 38412, part 8, nominal, BASF AG, 1988, rep. no.: 9/0843/88)
Based on the available data, 1-ethylpiperazine (CAS 5308-25-8) is considered with high probability to be acutely not harmful to aquatic organisms.
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