Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:
Migrated from Short description of key information:
Structural analogues like EDTA-FeNa, EDTA-CuNa2 and DTPA-FeHNa have not shown any skin sensitisation potential, i.e. read-across from supporting substance (structural analogue or surrogate). In addition, EDTA-CaNa2 is not irritating to the skin and because of its structure, EDTA-CaNa2 is expected to have low skin penetration (see read across document in section 13).

Justification for selection of skin sensitisation endpoint:
This endpoint has been waived because of sufficient information available for other metal chelates of EDTA.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

Because EDTA-CaNa2 is not considered to be a skin sensitiser it is not expected that it would be a respiratory sensitiser as all respiratory sensitisers tested have shown skin sensitising properties in skin sensitisation tests.


Justification for selection of respiratory sensitisation endpoint:
No study available

Justification for classification or non-classification

Because EDTA-CaNa2 is not considered to be a skin sensitiser no classification is needed for this endpoint.