Registration Dossier
Registration Dossier
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EC number: 400-410-3 | CAS number: 25485-88-5
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Cyclohexyl Salicylate
- IUPAC Name:
- Cyclohexyl Salicylate
- Details on test material:
- Cyclohexyl Salicylate Lot No. PE00016705, Purity 100%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- activated sludge
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 3 h
Results and discussion
Effect concentrations
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- All tested concentrations (1 to 100 mg/l) produced inhibitions below 50%.
Therefore:
The EC50 (3 hours) of Cyclohexyl Salicylate FAB is > 100 mg/l.
NOEC appears to be at 31.6 mg/l.
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