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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature. Original report not available.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Unnamed
Year:
1999
Reference Type:
secondary source
Title:
Fragrance raw materials monograph
Author:
Anonymous
Year:
1982
Bibliographic source:
food and Chemical toxicology, V20, 1982
Reference Type:
publication
Title:
No information
Author:
Moreno
Year:
1978

Materials and methods

Principles of method if other than guideline:
acute dermal toxicity on guinea pigs
GLP compliance:
no
Test type:
standard acute method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Methyl Hexanoate (Caroic)
- Analytical purity: not given

Test animals

Species:
guinea pig
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
no data
Doses:
5000 mg/kg
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion