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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The 48h-EC50 was 52 mg/L based on analytically confirmed nominal concentrations (95% confidence interval between 45 and 64 mg/L).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
52 mg/L

Additional information

Short-term toxicity to aquatic invertebrates Daphnia magna was assessed according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test), and EU Method C.2 (Acute Toxicity for Daphnia) and in compliance with GLP. Daphnia were exposed under static conditions to the substance at concentrations of 4.6, 10, 22, 46, and 100 mg/L in freshwater.

The test was performed with 5 daphnia per vessel. For each concentration, the percentage of immobilisation at 24 hours and 48 hours was recorded, and test concentrations were confirmed by HPLC analysis.

After 48 hours NOEC was 22 mg/L and EC50 was 52 mg/L (nominal values).