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EC number: 237-486-0
CAS number: 13814-96-5
Testing of lead
bis(tetrafluoroborate) is considered to be justified, since the
substance is classified as corrosive by worst case based on the pH of <2
in aqueous solution. Nevertheless, animal testing for sensitisation
potential is not scientifically justifiable as it would not provide any
further information considered being relevant for human risk assessment.
and human data on various lead substances exist which stated that
neither skin nor respiratory sensitisation are observed. Therefore, read
across from lead compounds (in special from water soluble substances)
and tetrafluoroborate salts is considered to be justified. The toxicity
of lead bis(tetrafluoroborate) may reasonably be considered to be
determined by the availability of lead2+and tetrafluoroborate-.
Aa a first surrogate for bioavailability, the water solubility may be
used. Lead chloride is water soluble up to 10 g/L at 20°C,
tetrafluoroborate salts (e.g potassium tetrafluoroborate, sodium
tetrafluoroborate and triethylmethylammonium tetrafluoroborate) from 1.3
g/L at 20°C (KBF4) up to 2000 g/L at 20°C (TEMABF4).
The water solubility of lead bis(tetrafluoroborate) is > 500 g/L at
20°C. Therefore, such read-across is considered to be feasible without
given the lack of sensitising properties of lead compounds in general
and of tetrafluoroborate salts especially, lead
compounds and tetrafluoroborate salts do not appear to pose any risk of
sensitisation, and therefore no classification for these endpoints is
Classification and labelling of lead
bis(tetrafluoroborate) is considered not to be justified, due to the
reasons given above.
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