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EC number: 930-592-4 | CAS number: -
Testing was performed according to the Method B.3 Acute Toxicity (Dermal), Council Regulation (EC) No.440/2008, published in O.J. L 142, 2008.
According to the results of study, the value of LD50 (dermal) of the test substance for rats of both sexes was higher than 2000 mg/kg of body weight.
The study was performed as limit test: two groups of animals - 5 males and 5 females and the dose of 2000 mg/kg of body weight. The pre-test was performed with 1 male and 1 female from each group. After clinical observation of these pilot animals for 2 days after test substance application, the other animals of the group were dosed. The test substance was applied on the shaved skin of the test animals in delivered form for 24 hours. The test animals were observed 14 days after application, afterwards they were sacrificed, and the necropsy for macroscopic examination of the organs was performed.
The test substance applied at the dose of 2000 mg/kg of body weight did not cause death of animals. No clinical signs of intoxication were observed in all animals. No irritation on the skin was observed in all animals. No macroscopic change was diagnosed during pathological examination in all animals.
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