Registration Dossier
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EC number: 237-048-9 | CAS number: 13597-46-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The most critical LC50 for freshwater fish was a 96-h LC50 for SeO2 for fathead minnow (Pimephales promelas) of 2060 µg Se/L. The most critical LC50 for marine fish was a 96-h LC50 of 3300 µg Se/L for the anadromous fish species Morone saxatilis (striped bass) obtained from a test in brackish water with Na2SeO3.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2 060 µg/L
Marine water fish
Marine water fish
- Effect concentration:
- 3 300 µg/L
Additional information
For acute toxicity to fish, a total of 56 sources were identified as possibly relevant. After review, 54 studies were retained as relevant (including 4 reviews). Only 6 studies were assigned a Klimisch 1 (reliable) or Klimisch 2 score (reliable with restrictions). Reliable data were available for SeO2, Na2SeO3 and Na2SeO4 and for 8 freshwater species from 6 different families (Pimephales promelas, Carassius auratus and Notemigonus crysoleucas (Cyprinidae), Jordanella floridae (Cyprinodontidae), Lepomis macrochirus (Centrarchidae), Ictalurus punctatus (Ictaluridae), Salvelinus fontinalis (Salmonidae), Stizostedion vitreum (Percidae)) and 2 marine species (from 2 families: Pargus major (Sparidae), and Morone saxatilis (Moronidae)). All results are based on added dissolved elemental Se concentrations.
For freshwater species, the LC50 values ranged from 2060 to 28460 µg Se/L. The lowest LC50 represented a 96-h LC50 for SeO2 for fathead minnow, Pimephales promelas (Cardwell et al., 1976). The highest LC50 was a 96-h LC50 for bluegill (Lepomis macrochirus) from a toxicity test from the same study with the same test substance.
For brackish/saltwater species, reliable LC50 values were found between 3300 and 76000 µg Se/L. The lowest LC50 was a 96-h LC50 for the anadromous fish species Morone saxatilis (striped bass) resulting from a toxicity test in brackish water with Na2SeO3 as test substance (Chapman, 1992). The highest LC50 represented a 96-h LC50 for red seabream (Pargus major) obtained from a toxicity test in natural filtered uncontaminated seawater with Na2SeO4 as test substance (Takayanagi, 2001).
For freshwater fish, the data are inconclusive with regard to the question whether selenite compounds are more toxic than selenate compounds. This is mainly due to the low number of available effect concentrations for both selenium forms. Even when the data for SeO2 (which forms H2SeO3 upon dissolution in water) are considered as selenite data, still no conclusion can be made. For marine fish however, data are available from two different studies in which a single fish species was exposed to either selenite or selenate. From these data it can be concluded that selenite is more toxic than selenate to the two fish species under consideration.
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