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Ecotoxicological information

Toxicity to terrestrial arthropods

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Description of key information

Geuijen (2001) was considered adequate and reliable for use in assessing the toxicity of 2,4,6-tribromophenol in terrestrial arthropods. The study was performed to both OECD guideline 213 and 214, the study was also GLP compliant.

Key value for chemical safety assessment

Additional information

Reference: Geuijen, W.H.C. (2001)

Reliability: 1

Results: Some mortality was observed in the contact test with tribromophenol in the honey bee (<10%), however, this was less than the level of mortality observed in the solvent control. Mean Abbott corrected cumulative mortality was 0% at all doses. Contact LD50 was concluded to be above 100 ug/bee. The NOEC was set at the highest tested dosage, i.e. 100 ug/bee.

Dosing orally, tribromophenol induced some mortality (<10%). At the highest tested dosage (actual dosage 112 ug/bee) mortality was 7% after 48 hours. There was no mortality in the solvent control. Hence, the oral LD50 for Tribromophenol is above 112 ug/bee. The NOEC was set at the highest tested dosage, i.e. 112 ug/bee.

Duration

Endpoint

Effect conc.

Nominal/Measured

Conc. based on

Basis for effect

Remarks (e.g. 95% CL)

96 h

NOEC

100 µg per animal

nominal

test mat.

mortality

Contact test

96 h

LC50

> 100 µg per animal

nominal

test mat.

mortality

Contact test

48 h

NOEC

112 µg per animal

nominal

test mat.

mortality

Oral

48 h

LD50

> 112 µg per animal

nominal

test mat.

mortality

Oral test

The following information is taken into account for effects on soil arthropods for the derivation of PNEC:

Geuijen (2001) was considered adequate and reliable for use in assessing the toxicity of 2,4,6-tribromophenol in terrestrial arthropods. The study was performed to both OECD guideline 213 and 214, the study was also GLP compliant.