Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

oxidising liquids
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion

Executive summary:




Name of substance: Benzene, ethenyl, ar–bromo derivs


Omitted study: A21: Oxidising properties (liquids)




The oxidising properties were predicted based structural considerations rather than by formal testing using Method A21 of Council Regulation (EC) No 440/2008.Screening procedures represent an intelligent testing strategy (ITS) for oxidising properties. In accordance with the Guidance on information requirements and chemical safety assessment, if ITS is applied correctly to the oxidising properties endpoint, only substances for which it is suspected will give a positive result in one of the oxidising properties tests need to be tested.




The structure of the substance was assessed for chemical groups that would imply oxidising properties. Common examples of such groups are nitrates, nitrites, organic nitro compounds, metal oxides, metal oxometallates, N-halogen compounds, N-haloimides, difluoroaminos, difluoroaminopolynitroaryls and oxohalogen compounds (e.g. hypofluorites, perchlorates, bromates and iodites).




A review of the structure suggests that there are no chemical groups present that would imply oxidising properties.




Based on the known chemical and physical properties of the substance and its chemical structure, a negative result is predicted for the A21 Oxidising Properties liquids test of Council Regulation (EC) No 440/2008.As such it is considered justified to omit the test.




Bretherick (1999) Bretherick’s Handbook of Chemical Reactive Hazards: An Indexed Guide to Published Data, 6th Edition (2 volume set).


Table R.7.1-29 of Chapter R.7a: Endpoint specific guidance within ECHA REACH Guidance on Information Requirements and Chemical Safety Assessment.