Registration Dossier
Registration Dossier
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EC number: 200-453-6 | CAS number: 60-09-3
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: well documented publication which meets basic scientific principles.
Data source
Reference
- Reference Type:
- publication
- Title:
- Actual survey on TLm (median tolerance limit) values of environmental pollutants, especially on amines, nitrilens, aromatic nitrogens compounds and artificial dyes
- Author:
- Tonogai Y et al.
- Year:
- 1 982
- Bibliographic source:
- Journal of Toxicological Sciences 7:193-203
Materials and methods
- Principles of method if other than guideline:
- The TLm (Median tolerance limit) was carried out according to Japanese industrial standards (Japanese Industrial Standards Comittee, 1971).
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-aminoazobenzene
- EC Number:
- 200-453-6
- EC Name:
- 4-aminoazobenzene
- Cas Number:
- 60-09-3
- Molecular formula:
- C12H11N3
- IUPAC Name:
- 4-[(E)-2-phenyldiazen-1-yl]aniline
- Details on test material:
- I- Name of test material (as cited in study report): p-aminoazobenzene
- Analytical purity: not stated,
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Details on test solutions:
- Chemical substances were dissolved in water and neutralized, if necessary. Some Substances were dissolved in 1 ml ethanol, and then diluted with water.
Test organisms
- Test organisms (species):
- Oryzias latipes
- Details on test organisms:
- Fish of the same age (ca. 2 cm length; 0.2 g weight) for each experiment.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 25°C
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.7 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1.7 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
