Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-323-3 | CAS number: 908020-52-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
In a GLP-compliant OECD guideline 111 study, less than 10% degradation of the EEA ion of EEA-NH4 was observed after 5 days at 50 ºC at all pH concentrations (TNO Quality of Life, 2008a). The EEA ion of EEA-NH4 was considered hydrolytically stable at pH 4.0, pH 7.0 and pH 9.0.
No studies are available on photolysis in water or atmospheric degradation.In a GLP-compliant, OECD 301C Modified MITI test biodegradation of EEA-NH4 was tested using activated sludge prepared from several sampling sites (return sludges from both city and industrial sewage treatment plants and surface water and surface soil). The test item was found to be not readily biodegradable after 28 days (Kurume Laboratory, 2005).
Simulation studies were not performed.
The degradation rate constants used in the assessment are:
Degradation for hydrolysis: 6.93E-07 d-1
Degradation for photolysis: 6.93E-07 d-1
Degradation rate in air: 0 d-1
Degradation rate in the STP: 0 d-1
Degradation rate in surface water: 1.39E-06 d-1
Degradation rate in aerated sediment: 6.93E-07 d-1
Degradation rate in soil: 6.93E-07 d-1
The log Koc of the EEA ion of EEA-NH4 could not be determined using the HPLC-method. Therefore, the organic carbon-water partitioning coefficient (Koc) was calculated from the octanol-water partition coefficient (log Kow) using the equation from EUSES (predominantly hydrophobics). The calculated log Koc is 11.4 L/kg (log value = 1.06) from a log Kow of 1.18. This predicted value is used in the assessment. Further studies on transport and distribution of EEA-NH4 in the environment are not available.
The bioconcentration of EEA-NH4 in fish was studied according to OECD guideline 305 (Kurume Laboratory, 2006a). Bioaccumulation of EEA-NH4 in Japanese carp (Cyprinus carpio) was tested at 2 and 20 μg/L under flow-through conditions at 25oC (nominal concentrations). The BCFs of EEA-NH4 were not more than 5.8 at 2 μg/L and 0.59 at 20 μg/L. Because the BCFs were below 100 it was assumed that steady state was reached within 28 days.The BCFs indicate a low potential for bioconcentration. The BCF of 5.8 is used in the assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
