## Registration Dossier

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** EC number: 482-410-3 | CAS number: - **

- Life Cycle description
- Uses advised against

- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity

- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour

- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms

- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information

- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

## Vapour pressure

### Administrative data

- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing was conducted between 20 February 2008 and 03 March 2008.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.

### Data source

##### Reference

- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2008
- Report Date:
- 2008

### Materials and methods

##### Test guideline

- Qualifier:
- according to
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- yes

- GLP compliance:
- yes (incl. certificate)
- Remarks:
- Work described was performed in compliance with UK GLP standards (Schedule 1, Good Laboratory Practice Regulations 1999 (SI 1999/3106 as amended by SI 2004/0994)). Date of inspection: 21/08/2007. Date of signature: 29/04/2008
- Type of method:
- effusion method: vapour pressure balance

#### Test material

##### Reference

- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- Sponsor's identification :Hatcol 1760

Description : clear colourless slightly viscous liquid

Purity : >99%

Date received : 04 February 2008

Storage conditions :room temperature, in the dark

### Results and discussion

##### Vapour pressure

- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa

##### Transition / decomposition

- Transition / decomposition:
- no

#### Any other information on results incl. tables

**Run 1 **

A plot of Log_{10}(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 1 gives the following statistical data using an unweighted least squares treatment.

Slope -7026.925

Standard deviation in slope 212.789

Intercept 16.320

Standard deviation in intercept 0.533

The results obtained indicate the following vapour pressure relationship:

Log_{10}(Vp (Pa)) = -7026.925/temp(K) + 16.320.

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -7.248.

**Run 2 **

A plot of Log_{10}(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 2 gives the following statistical data using an unweighted least squares treatment.

Slope -8784.915

Standard deviation in slope 278.657

Intercept 20.666

Standard deviation in intercept 0.699

The results obtained indicate the following vapour pressure relationship:

Log_{10}(Vp (Pa)) = -8784.915/temp(K) + 20.666.

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -8.799.

**Run 3**

A plot of Log_{10}(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 gives the following statistical data using an unweighted least squares treatment.

Slope -8480.343

Standard deviation in slope 469.643

Intercept 19.878

Standard deviation in intercept 1.177

The results obtained indicate the following vapour pressure relationship:

Log_{10}(Vp (Pa)) = -8480.343/temp(K) + 19.878.

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -8.565.

**Run 4**

A plot of Log_{10}(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.

Slope -8080.251

Standard deviation in slope 238.093

Intercept 18.860

Standard deviation in intercept 0.598

The results obtained indicate the following vapour pressure relationship:

Log_{10}(Vp (Pa)) = -8080.251/temp(K) + 18.860.

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -8.242.

**Run 5**

A plot of Log_{10}(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 5 gives the following statistical data using an unweighted least squares treatment.

Slope -7603.848

Standard deviation in slope 399.061

Intercept 17.656

Standard deviation in intercept 1.002

The results obtained indicate the following vapour pressure relationship:

Log_{10}(Vp (Pa)) = -7603.848/temp(K) + 17.656.

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -7.847.

**Run 6**

A plot of Log_{10}(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 6 gives the following statistical data using an unweighted least squares treatment.

Slope -7039.013

Standard deviation in slope 313.177

Intercept 16.190

Standard deviation in intercept 0.786

The results obtained indicate the following vapour pressure relationship:

Log_{10}(Vp (Pa)) = -7039.013/temp(K) + 16.190.

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -7.419.

**Run 7**

A plot of Log_{10}(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 7 gives the following statistical data using an unweighted least squares treatment.

Slope -6714.109

Standard deviation in slope 287.395

Intercept 15.359

Standard deviation in intercept 0.721

The results obtained indicate the following vapour pressure relationship:

Log_{10}(Vp (Pa)) = -6714.109/temp(K) + 15.359.

The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -7.160.

**Summary of Results **

Run | Log |

1 | -7.248 |

2 | -8.799 |

3 | -8.565 |

4 | -8.242 |

5 | -7.847 |

6 | -7.419 |

7 | -7.160 |

Mean | -7.897 |

Vapour Pressure | 1.268 x 10 |

The test material did not change in appearance under the conditions used in the determination.

### Applicant's summary and conclusion

- Conclusions:
- The vapour pressure of the test material has been determined to be 1.3 x 10-8 Pa at 25ºC.
- Executive summary:
**Method**The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using Method A4 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).

**Conclusion**The vapour pressure of the test material has been determined to be 1.3 x 10

^{-8}Pa at 25ºC.

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