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EC number: 453-230-2 | CAS number: -
An acute dermal Irritation/Corrosion test according to OECD 404 was performed. The test item was semi-occlusively applied to the skin on 3 female New Zealand White Rabbits HsdIf:NZW and held in contact throughout a 4 hour period. The test item showed slight irritant effects on the intact skin after a contact time of 4 hours. All animals showed erythema grade 1 at the 1 h, 24 h, 48 h, 72 h, 96 h, 120 h as well as 144 hours readings after removal of the dressing. No signs of irritation were recorded for any animals at the 168 hours readings. No other clinical signs of toxicity were found. There were no significant body weight changes during the contact and observation period. Therefore, the test item does not have to be classified and has no obligatory labelling requirement for skin irritation.
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