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EC number: 439-840-1
CAS number: 20846-91-7
In a GLP study conducted according to OECD Guideline 202, the 48-h NOEC of trisodium EDDS for mobility and swimming behaviour of the freshwater crustacean, Daphnia magna, was 1000 mg/L (the highest tested concentration) and 320 mg/L, respectively. After 48 h exposure, all daphnids were mobile at all the tested concentrations, therefore the 48-h EC50 would be >1000 mg/L.
In a GLP study conducted according to OECD
Guideline 202, the acute toxicity of trisodium EDDS to the freshwater
crustacean, Daphnia magna, was assessed. The test was carried out with 4
beakers each containing 5 daphnids for each test concentration, and the
test solutions were not replaced. The exposure duration was 48 h. The
animals were assessed for mobility and condition (swimming behaviour,
colour, respiratory function or other visually observable morphological
or behavioural criterion) at 0, 24 and 48 h. The nominal concentrations
tested were 0, 100, 180, 320, 560 and 1000 mg/L. All test solutions were
completely clear (visually assessed) throughout the test.
After 48 h exposure all daphnids were mobile
at all the tested concentrations (therefore the 48-h EC50 would be >1000
mg/L). Regarding swimming behaviour, at 560 and 1000 mg/L the daphnids
swam slower with irregular movements, and at 1000 mg/L they were paler
in appearance than controls. Therefore, under the conditions of this
study, the 48-h NOEC for trisodium EDDS for mobility and behaviour of
Daphnia magna were 1000 mg/L and 320 mg/L, respectively (Hooftman and
van Drongeien-Sevenhuijsen, 1993).
No data in marine invertebrates are
currently available for EDDS acid or its trisodium salt.
trisodium EDDS is considered relevant to use for understanding the
potential toxicity to aquatic invertebrates of EDDS acid, and is
acceptable for using as read-across information].
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