Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 439-840-1 | CAS number: 20846-91-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In a GLP study conducted according to OECD Guideline 202, the 48-h NOEC of trisodium EDDS for mobility and swimming behaviour of the freshwater crustacean, Daphnia magna, was 1000 mg/L (the highest tested concentration) and 320 mg/L, respectively. After 48 h exposure, all daphnids were mobile at all the tested concentrations, therefore the 48-h EC50 would be >1000 mg/L.
Key value for chemical safety assessment
Additional information
In a GLP study conducted according to OECD Guideline 202, the acute toxicity of trisodium EDDS to the freshwater crustacean, Daphnia magna, was assessed. The test was carried out with 4 beakers each containing 5 daphnids for each test concentration, and the test solutions were not replaced. The exposure duration was 48 h. The animals were assessed for mobility and condition (swimming behaviour, colour, respiratory function or other visually observable morphological or behavioural criterion) at 0, 24 and 48 h. The nominal concentrations tested were 0, 100, 180, 320, 560 and 1000 mg/L. All test solutions were completely clear (visually assessed) throughout the test.
After 48 h exposure all daphnids were mobile at all the tested concentrations (therefore the 48-h EC50 would be >1000 mg/L). Regarding swimming behaviour, at 560 and 1000 mg/L the daphnids swam slower with irregular movements, and at 1000 mg/L they were paler in appearance than controls. Therefore, under the conditions of this study, the 48-h NOEC for trisodium EDDS for mobility and behaviour of Daphnia magna were 1000 mg/L and 320 mg/L, respectively (Hooftman and van Drongeien-Sevenhuijsen, 1993).
No data in marine invertebrates are currently available for EDDS acid or its trisodium salt.
[Data on trisodium EDDS is considered relevant to use for understanding the potential toxicity to aquatic invertebrates of EDDS acid, and is acceptable for using as read-across information].
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
