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EC number: 470-080-3
CAS number: -
1-((2-Butyloctyloxymethyl)-2-(3,4-dihydro-isoquinolinium-2-y l)ethyl)sulfate was tested for its acute toxicity to Daphnia magna according to OECD guideline 202 and EU method C.2. The 48 hour EC50 value was > 3.73 mg/L based on the mean of analytically determined concentrations.
l)ethyl)sulfate was tested for its acute toxicity to Daphnia magna
according to OECD guideline 202 and EU method C.2. Groups of five
daphnias were exposured to test item at the measured analytical
concentrations of 0 (control), 0.146, 0.285, 0.624, 1.33, 2.58, 3.73
mg/L. The test was performed in concentrations up to the limit of
solubility of the test substance in water. The test concentrations were
selected on the basis of the non-GLP range finding part of the study.
The water solubility of the test substance is 2.5 mg/L (20°C). The
initial concentrations of the saturated solution was 4.45 mg/L and thus
above the water solubility of 2.5 mg/L. During the 48 h testing period a
marked decrease of the test concentrations to 50 – 79 % of the initial
concentrations was observed. Therefore the results are based on the mean
of the analytically determined concentrations of the exposure period.
The mean of the highest tested concentration (3.73 mg/L) is still above
the water solubility of the test substance (2.5 mg/L). The following
effect concentrations (mg/L) were obtained based on mean measured
EC0 (48 h) = 2.58 mg/L
EC50 (48 h) > 3.73 mg/L
EC100 (48 h) > 3.73 mg/L.
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