Registration Dossier

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 211 (Daphnia magna Reproduction Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
Batch: C421000826
Purity: 100%

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no
Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: None

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
21 d

Test conditions

Hardness:
250 mg CaCO3/L
Test temperature:
The water temperature was between 18 and 21°C during the test period
pH:
The pH ranged from 7.5 - 8.0
Dissolved oxygen:
8.1 mg/l - 9.2 mg/l
Reference substance (positive control):
not specified

Results and discussion

Effect concentrations
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
>= 100 mg/L

Applicant's summary and conclusion

Executive summary:

Taking into account the reproduction rates and survival of the test animals, the highest nominal concentration of ucb6474 tested without toxic effects after the exposure period of 21 days was 100 mg/l. The 21 -day NOEC might be higher, but concentrations above 100mg/l are not tested.