Registration Dossier
Registration Dossier
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EC number: 427-720-1 | CAS number: 26364-65-8
Dissociation constant
Administrative data
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study according to OECD 112
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 427-720-1
- EC Name:
- -
- Cas Number:
- 26364-65-8
- Molecular formula:
- C4H5N3S
- IUPAC Name:
- [(1,3-thiazolidin-2-ylidene)amino]formonitrile
- Details on test material:
- name: Cyanamide, (4,5-dihydroxy-2-thiazolyl)-
molecular formula: C4 H5 N3 S
molecular weight: 127.2
physical state: solid
analytical purity: 99.8 %
Constituent 1
Results and discussion
- Dissociating properties:
- no
Dissociation constant
- pKa:
- 10
- Remarks on result:
- other: at room temperature
Any other information on results incl. tables
The titration curves obtained from the titrations with sodium hydroxide show potential jumps
corresponding to a neutralisation reaction due to the existence of an acidic centre in the molecule of CIT
with a calculated pKa value of 10.0.
Applicant's summary and conclusion
- Conclusions:
- CIT has a pKa value fo 10.00 in aqueous solutions.
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