Registration Dossier
Registration Dossier
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EC number: 469-110-8 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
No experimental data is available for the registered substance. However, based on the high log Kow value (estimated logKow >10) and based on the Guidance document on PBT assessment R.11, this high logKow predicts the aquatic BCF value to be below the threshold value for vB (5000 L/kg) and B (2000 L/kg). Therefore, the substance would be considered to have an expected low bioavailability and thus a limited bioaccumulation potential.
In order to confirm this consideration, an analogue was found with a very low experimental BCF.
This analogue was considered appropriate for read-across and probably worst case for bioconcentration than the registered substance (lower MW and thus expected higher bioavailability). It is therefore deemed appropriate to use the bioconcentration data of this analogue to evaluate the bioaccumulation potential of the registered substance.
The low potential for bioaccumulation was additionally confirmed by the result of the QSAR from EPIWEB 4.0 run on the main component of the registered substance.
All information above can be combined in a weight-of-evidence that the registered substance is deemed to have limited bioaccumulation potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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