Registration Dossier

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006
Report Date:
2006

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals / tissue source

Species:
rabbit
Strain:
New Zealand White

Results and discussion

Results of in vivo studyopen allclose all
Irritation parameter:
conjunctivae score
Basis:
animal #1
Time point:
other:
Score:
1
Max. score:
2
Remarks on result:
other:
Irritation parameter:
conjunctivae score
Basis:
animal #2
Time point:
other:
Score:
1
Max. score:
2
Remarks on result:
other:
Irritation parameter:
conjunctivae score
Basis:
animal #3
Time point:
other:
Score:
1.67
Max. score:
2
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
animal #1
Time point:
other:
Score:
0.67
Max. score:
1
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
animal #2
Time point:
other:
Score:
0
Max. score:
1
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
animal #3
Time point:
other:
Score:
0.33
Max. score:
1
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
animal #1
Time point:
other:
Score:
0
Max. score:
0
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
animal #2
Time point:
other:
Score:
0
Max. score:
0
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
animal #3
Time point:
other:
Score:
0
Max. score:
0
Remarks on result:
other:
Irritation parameter:
iris score
Basis:
animal #1
Time point:
other:
Score:
0
Max. score:
0
Remarks on result:
other:
Irritation parameter:
iris score
Basis:
animal #2
Time point:
other:
Score:
0
Max. score:
0
Remarks on result:
other:
Irritation parameter:
iris score
Basis:
animal #3
Time point:
other:
Score:
0
Max. score:
0
Remarks on result:
other:

Applicant's summary and conclusion