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EC number: 473-390-7
CAS number: -
The toxicity of FC-770 to Danio rerio (zebrafish) was assessed in a
semi-static test conducted according to OECD TG203. The test was
performed as a limit test after a rangefinding test indicated no
toxicity in water accomodated fractions (WAFs) made using loading rates
of 0.10, 1, and 10 mg/L. The limit test used a WAF made with a loading
rate of 100 mg/L. FC-770 concentrations in 24 hour-old test solutions
were below the limit of quantitation. Because concentrations could not
be stably maintained, the average of the geometric means of the fresh
and 24-hour old solutions at 0-24 hours and 72-96 hours was used to
establish a concentration of 0.096 mg/L in the exposed fish. No toxicity
was observed in the exposed fish. Due to the low solubility of the test
substance in water combined with its volatility, concentration levels
that might be acutely
toxic for zebrafish could not be reached. The LC50s of FC-770 to
Danio rerio was >0.096 mg/L. The NOEC was 0.096 mg/L.
The study was conducted under accepted guidelines and according to GLP
criteria. The concentration of FC-770 could not be maintained above the
limit of quantitation. However, reasonable efforts were made to obtain
and maintain the highest possible concentration over the whole test
duration. Therefore, the study is classified as reliable with
Test organism weight/length: 0.43 g / 3.2 cm
Test Type: Semi-Static
LC50: >0.096 mg/L 95% C.I.: NA
NOEC: 0.096 mg/L Probit Slope: NA
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