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EC number: 411-950-4 | CAS number: 96562-58-2 DHPPME; MAK-ME; MEHPOPS; R-MAQ-ME
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
Campbell et al. (1993): Under the conditions of this study, the log Pow was determined to be 1.29 at 22 °C when tested at pH 4, 7 and 9.
Caesar (1991): Under the conditions of this study, the partition coefficient of the test material at 25 °C was determined to be 25.2 and the log Pow was determined to be 1.40.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.29
- at the temperature of:
- 22 °C
Additional information
Two studies are available to address this endpoint and both are considered to be key as the data are equally reliable. The studies were assigned a reliability score of 1 in accordance with the criteria for assessing data quality set forth by Klimisch et al. (1997).
Campbell et al. (1993)
The partition coefficient of the test material was investigated in a study which was performed in accordance with the standardised guidelines OECD 107 and EU method A.8 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Investigation of the octanol:buffer partition coefficient was carried out at 22 ± 0.5 °C using the flask method. Aliquots from each layer were analysed along with standard and quality control samples. The test was performed using buffered aqueous phases at pH 4, 7 and 9. An approximately 1 mg/mL solution of test material in pre-saturated octanol was accurately prepared for each of the aqueous phases under investigation.
Screw capped tubes were prepared containing 3, 5 and 6 mL of stock solution with 6, 5 and 3 mL of the relevant aqueous phase, respectively. Samples were prepared in duplicate. The tubes were then manually inverted 100 times prior to centrifugation at 3000 rpm for 15 min to separate the layers. Aliquots were then taken from each phase for analysis.
The mean values for the partition coefficient at pH 4.0, 7.0 and 9.0 were 19.40, 19.44 and 19.48, respectively. Log Pow values were 1.29, 1.29 and 1.29, respectively.
Under the conditions of this study, the log Pow was determined to be 1.29 at 22 °C when tested at pH 4, 7 and 9.
Caesar (1991)
The partition coefficient of the test material was investigated in accordance with the standardised guideline EU Method A.8 under GLP conditions using the flask method.
Known amounts of the test material were weighed into 25.0 mL of 1-octanol, 25 mL of water was added and the mixture was allowed to come to equilibrium. After the phases had separated the aqueous phase was removed, centrifuged at about 3000 rpm for about 30 minutes, and the lower aqueous phase was removed.
The latter was extracted with chloroform and the concentration of the test material in the chloroform extract was determined through gas chromatography using an external standard.
The values obtained were recalculated for the aqueous phase from which the extractions had been carried out. All measurements were done at ambient temperature (25 °C).
Under the conditions of this study, the partition coefficient of the test material at 25 °C was determined to be 25.2 and the log Pow was determined to be 1.40.
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