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EC number: 429-780-4 | CAS number: 129738-34-7
With the test material CC-5-V one oral acute toxicity study was conducted. The results show no mortality, no body weight change and no other signs of toxicity. No further acute toxicity studies for inhalative or dermal administration are available.
In an acute oral toxicity study (key - CC-5 -V - T14191), one group of fasted, young adult Wistar rats (5/sex) were given a single oral dose of CC-5 -V prepared with liquid paraffin solution (100 g/L) as vehicle at a dose of 2000 mg/kg bw and observed for 14 days. The following results were obtained:
Males > 2000 mg/kg bw
Females > 2000 mg/kg bw
Combined > 2000 mg/kg bw
No mortality occurred in this limit test.
CC-5 -V is of low toxicity based on the LD50 in male and female rats.
Besides wet anal region observed on day one after treatment, there were no treatment related clinical signs, necropsy findings or changes in body weight.
Based on the results for acute oral and dermal toxicity in rats, CC-5 -V is considered to have no acute toxic potential. The expected LC50 values are higher than 2000 mg/kg bw after oral administration to rats.Therefore, CC-5 -V is not classified according to EU Directive 67/548/EC amended and repealed by EU Regulation No.1272/2008 and CLP.
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