Registration Dossier
Registration Dossier
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EC number: 266-719-9 | CAS number: 67564-91-4
Endpoint summary
Administrative data
Description of key information
Birds
Fenpropimorph was tested on mallard ducks (Anas platyrhynchos) and bobwhite quails (Colinus virginianus). The studies performed cover a broad range of biological endpoints, such as mortality, signs of toxicity, feed consumption, body weight, post-mortem examinations and various reproduction parameters. LD50 was determined to be > 2000 mg a.s./kg body weight (single dose application) and LC50 > 5000 mg a.s./kg diet (dietary feeding test). Two long-term avian reproduction studies were performed and resulted in NOEC-values of 45 mg a.s./kg feed and 333 mg a.s./kg feed, the highest concentrations tested.
Honeybees
Acute oral and contact toxicity of fenpropimorph were tested in bee toxicity studies, The LD50-values (48 h) were > 95.6 µg a.s./bee (oral) and > 100 µg a.s./bee (contact).
Earthworms
Effects of fenpropimorph have been tested on earthworms in a 14-day toxicity study up to 1000 mg a.s./kg. Fenpropimorph caused no earthworm mortality (LC50 > 1000 mg a.s./kg; NOEC = 1000 mg a.s./kg).
Microorganisms
Two laboratory studies of nitrogen and carbon transformation of fenpropimorph are existing (2013/1132395 (OECD 216) and 2013/1132394 (OECD 217)).
Exposure of fenpropimroph in a field soil up to test concentration of 12 mg/kg soil dry weight caused no adverse effects (deviation from control < 25 %) on neither the soil nitrogen transformation (measured as NO3-N production) nor the soil carbon transformation (measured as oxygen consumption) at the end of the 28-day incubation period (time interval 0-28).
Plants
Based on the results of the study conducted (BASF DocID 1999/11450) under worst case greenhouse conditions, it can be concluded, that applications of a fenpropimorph formulation (BAS 421 12 F) up to 0.75 L/ha (0.54 mg/kg) caused no damages to non-target terrestrial plants. At a rate of 2.25 L/ha caused less than 30 % plant weight reduction.
In terms of terrestrial ecotoxicity assessment the endpoints were converted into a 14d-NOEC of 0.54 mg/kg (based on 0.75 L/ha).
Non-target organisms
Additionally it shall be mentioned that in the publication ''Effects of pesticides on the reproduction of Hypoaspis aculeifer (Gamasida: Laelapidae) in the laboratory'' from the year 1995 from Paul H. Krogh the effects of fenpropimorph on the predacious mite H. aculeifer were investigated. During a test duration of 3 weeks a NOEC > 6.0 mg/kg was determined via a single species reproductive test system (no test guideline is available). Finnish Zoological and Botanical Publishing Board 1995, Acta Zool. Fennica 196:333-137; ISBN 951-9481-41-9
Additional information
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