Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
- Primary constituent: The BCF was predicted to be 381.4 L/kg ww by BCFBAF v3.01 (EPISUITE, 2013).
- Stearyl erucamide: The BCF of stearyl erucamide was predicted to be 113.1 L/kg ww by BCFBAF v3.01 (EPISUITE, 2013).
Bioaccumulation
No experimental study on bioaccumulation is available on the registered substance. The test material is identified as a UVCB therefore estimation through Quantitative Structure–Activity Relationship (QSAR) assessment is not an appropriate approach for the substance as a whole. To address the bioaccumulation endpoint a QSAR assessment, using the Estimation Programs Interface (EPI) SuiteTM BCFBAF v3.01, was completed as part of a weight of evidence approach on the primary constituent of the substance and an appropriate read across substance stearyl erucamide (CAS 10094-45-8).
Based on the above information, as a worst case example, the primary constituent presented the highest BCF value of 381.4 L/kg ww. This value has therefore been used through a supporting study to represent the bioaccumulation potential of the test material. Considering the registered substance properties the experimental log kow > 6,5 according to TG OECD 117 and predicted log Kow = 15,5 according to KOWWIN v1.68. Therefore, the registered substance falls outside the applicability of the model based on the log Kow descriptor (log Kow values > 11,2 max log kow value from training set compounds). The result of the estimation if therefore considered not to be completely reliable.
Considering that the substance does not fulfills the applicability domain of the QSAR, a bioacumulation test on fish is proposed according the TG OECD 305-III (see further explanation below).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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