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EC number: 636-728-6 | CAS number: 24690-44-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- QSAR Toolbox prediction for single chemical
- Year:
- 2 021
- Bibliographic source:
- QSAR Toolbox 3.4.0.17
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR Toolbox 3.4.0.17
- Version / remarks:
- Database version: 3.8.8/3.1.2
- GLP compliance:
- no
Test material
- Reference substance name:
- (4R)-4-[(4S)-2-oxo-1,3-dioxolan-4-yl]-1,3-dioxolan-2-one
- EC Number:
- 636-728-6
- Cas Number:
- 24690-44-6
- Molecular formula:
- C6H6O6
- IUPAC Name:
- (4R)-4-[(4S)-2-oxo-1,3-dioxolan-4-yl]-1,3-dioxolan-2-one
- Test material form:
- solid
Constituent 1
Results and discussion
In vitro
Results
- Irritation parameter:
- other: HT Version 20120101 phrasegroup_T46-1
- Vehicle controls validity:
- not applicable
- Negative controls validity:
- not applicable
- Positive controls validity:
- not applicable
- Remarks on result:
- no indication of irritation
- Other effects / acceptance of results:
- The prediction is based on 6 neighbours' values, 3 of them equal to prediction.
Prediction confidence is measured by the p-value = 1.90E-07 (very strong confidence)
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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