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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Details on test material:
- Name of test material (as cited in study report): WS400517
- Physical state: Off-white to pale yellow powder
- Analytical purity: Not applicable (complex mixture)
- Lot/batch No.: HH-09-168
- Expiration date of the lot/batch: 21 January 2011
- Storage condition of test material: Room temperature in the dark

Results and discussion

Water solubility
Key result
Water solubility:
< 1 mg/L
Conc. based on:
test mat.
Loading of aqueous phase:
100 mg/L
Incubation duration:
> 1 - <= 3 d
Temp.:
20 °C
pH:
6.3 - 6.9
Remarks on result:
not determinable because of methodological limitations
Details on results:
Water solubility values of 3 and 19 mg C/l at the low and high test loadings respectively were found. The higher apparent solubility at the higher test loading indicated that minor components or impurities would mainly have contributed to these values. Based on structure, the solubility of the test substance itself was anticipated to be much lower. Computer modelling ((WSKOWWIN, Version 1.41, U.S. Environmental Protection Agency) indicated a water solubility of much less than 1 mg/l for the major constituents of the test substance.

Applicant's summary and conclusion