Registration Dossier
Registration Dossier
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EC number: 271-587-0 | CAS number: 68585-78-4
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Reaction product of titanium tetraisopropanolate and Dioctyl Dihydrogen Diphosphate
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- Reaction product of titanium tetraisopropanolate and Dioctyl Dihydrogen Diphosphate
- Reference substance:
- Reaction product of titanium tetraisopropanolate and Dioctyl Dihydrogen Diphosphate
- Reference substance:
- Reaction product of titanium tetraisopropanolate and Dioctyl Dihydrogen Diphosphate
- Reference substance:
- Reaction product of titanium tetraisopropanolate and Dioctyl Dihydrogen Diphosphate
- Reference substance:
- Reaction product of titanium tetraisopropanolate and Dioctyl Dihydrogen Diphosphate
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The target substance is hydrolytically unstable with hydrolysis half-life less than 30 minutes. Hydrolysis products include 2 -propanol, phosphate ester and hydrated titanium dioxide. Titanium dioxide is an inorganic substance and consider not relevant for toxicity evaluation. The intrinsic short-, long-term toxicities of the target substance is based on the two organic hydrolysis products.
The ocatanol-water partition coefficients are 0.05 (log value) for the organic products. The target substance is therefore considered not persistent and no bioaccumulation potential.
Based on the lowest 72h EC50 to Desmodesmus subspicatus of 512 mg/l, and no other findings of carcinogenicity, mutagenicity, toxicity to reproduction and long-term toxicity to target organs, the target substance is considered non-toxic.
Based on the results of the structural analogue, the 72 hour EC50 for biomass is 1.45 mg/L. The 24-48 hour EC50 for growth rate is c. 2 mg/L. The 72 hour NOEC is 0.125 mg/L. This value is far greater than 0.01 mg/l. No other findings of carcinogenicity, mutagenicity, toxicity to reproduction and long-term toxicity to target organs, the target substance is considered non-toxic.
Reference
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