Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 600-386-6 | CAS number: 10305-38-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h) > 100 mg/L for Daphnia magna (OECD 202)
Key value for chemical safety assessment
Additional information
One study is available on the short-term toxicity of 3-(Hexyloxy)-1.2-propanediol (CAS No. 10305 -38 -1) to aquatic invertebrates. This key study was performed according to OECD guideline 202 and GLP (Bouwman, 2013). The test organism Daphnia magna was exposed to the test substance in a static system for 48 hours at nominal test concentrations of 0, 0.10, 1, 10 and 100 mg/L. Analyses of the samples taken during the study were based on total organic carbon, since it proved impossible to develop a specific analytical method to accurately measure 3-(Hexyloxy)-1.2-propanediol concentrations in aquatic samples. Results showed measured carbon concentrations of 63.6 and 62.3 mg/l in samples taken from nominally 100 mg/l at the start and the end of the 48-hour test period. These results showed that the measured concentration was stable and, based on a carbon content of 61%, actual concentrations were between 102 and 104% relative to nominal. Given these results, the effect parameters were based on nominal concentrations. No immobilisation was observed at any of the test concentrations, hence the EC50 was reported to be > 100 mg/L (nominal).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
