Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 855-228-0 | CAS number: 4497-59-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Explosiveness
Administrative data
- Endpoint:
- explosive properties of explosives
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 Jul - 12 Aug 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- UN Manual of Tests and Criteria: Part I: Classification procedures, test methods and criteria relating to explosives of Class 1
- Version / remarks:
- UN Manual of Tests and Criteria, rev. 7 (2019), Appendix 6 - Koenen test: UN-tests 1(b), 2(b) - Time / pressure test 1(c), 2(c)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 113 Screening test for thermal stability and stability in air
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Hess. Ministerium für Umwelt, Klimaschutz, Landwirtschaft und Verbraucherschutz, Wiesbaden, Germany
Test material
- Reference substance name:
- 1-(2,2,4-trimethyl-3,4-dihydroquinolin-l (2H)-yl)ethanone
- EC Number:
- 855-228-0
- Cas Number:
- 4497-59-0
- Molecular formula:
- C14 H19 N O
- IUPAC Name:
- 1-(2,2,4-trimethyl-3,4-dihydroquinolin-l (2H)-yl)ethanone
Constituent 1
Results and discussion
Small-scale preliminary tests
- Parameter:
- other: decomposition energy from DSC measurement in J/g
- Value:
- 550
- Remarks on result:
- other: several exothermal effects starting at 160 °C with an energy of up to 550 J/g in closed DSC-measurements
Results of test series for explosivesopen allclose all
- Test series:
- UN Test series 1
- Method:
- UN Test 1 (b): Koenen test
- Parameter:
- limiting diameter (mm)
- Result:
- negative, no explosion
- Remarks on result:
- other: No explosion was observed, the limiting diameter was less than 1 mm.
- Test series:
- UN Test series 1
- Method:
- UN Test 1 (c) (i): Time/pressure test
- Parameter:
- other: Pressure rise time
- Result:
- negative, no or slow deflagration
- Remarks on result:
- p = 2070 kPa: no
- Remarks:
- None of the three tests reached a pressure of 2070 kPa.
- Test series:
- UN Test series 2
- Method:
- UN Test 2 (b): Koenen test
- Parameter:
- limiting diameter (mm)
- Result:
- negative, no explosion
- Remarks on result:
- other: No explosion was observed, the limiting diameter was less than 1 mm.
- Test series:
- UN Test series 2
- Method:
- UN Test 2 (c) (i): Time/pressure test
- Parameter:
- other: Pressure rise time
- Result:
- negative, no or slow deflagration
- Remarks on result:
- p = 2070 kPa: no
- Remarks:
- None of the three tests reached a pressure of 2070 kPa.
- Test series:
- UN Test series 2
- Method:
- UN Test 2 (a): UN gap test
- Parameter:
- other: fragmentation
- Result:
- other: see remarks
- Remarks on result:
- neither a test for propagation of detonation nor a test for sensitivity to detonative shock is required because the exothermic decomposition energy of the organic substance is less than 800 J/g
Any other information on results incl. tables
Thermal stability
Two DSC measurement in closed
glass crucibles showed an endothermal effect in the temperature range 70
-105 °C and two exothermal effects in the overall temperature range of
210 - 480 °C with a maximum energy release of 550 J/g. The course of the
baseline in the upper temperature range was ambiguous, this could have
been caused by a pressure rise. Due to this, the measurement was
repeated in high pressure crucibles.
One DSC measurement in high pressure crucibles showed an endothermal effect in the temperature range 70 - 100 °C and several exothermal effects in the overall temperature range 160 - 500 °C with an energy release of 212 J/g.
The results are summarized in the Table below:
Ident-No. | Weight / mg | Final temperature / °C | Temperature range / °C | Type of effect | Energy / J/g |
39147 | 11.61 | 500 | 70 - 105 220 - 250 255 - 460 |
Endothermal Exothermal Exothermal |
n.r. 4 546 |
39150 | 11.95 | 500 | 70 - 100 210 - 250 340 - 480 |
Endothermal Exothermal Exothermal |
n.r. 7 484 |
39156 | 16.56 | 500 | 70 - 100 160 - 260 275 - 365 375 - 500 |
Endothermal Exothermal Exothermal Exothermal |
n.r. 30 28 154 |
n.r.: not relevant
The heat of decomposition was above 500 J/g and below 800 J/g. Therefore, additional tests have to be performed for a classification or an exclusion as explosive substance according to UN Manual of Tests and Criteria, revision 7 (2019).
As the heat of decomposition was below 800 J/g and the test item is an organic substance, the next tests would be Koenen-test according to UN 1 (b)/2 (b) and Time-Pressure test according to UN 1 (c)/2 (c).
Koenen test
The Koenen test was started
with a diameter of 5 mm and subsequently continued with 3 mm, 2 mm, 1.5
mm and 1 mm. The physical state of the test item (solid) excludes the
enrichment of high-energy components caused by evaporation of volatile
solvents. Therefore, an explosion with larger nozzles could be excluded.
7 tests were performed. Tests were performed with a circular nozzle
plate with a hole of varying diameters.The results are shown in Table
below.
Amount / g | Diameter of orifice / mm | t1 / s | t2 / s | Reaction | Effect |
23.1 | 5 | 73 | > 300 | Flame | o |
23.1 | 3 | 74 | > 300 | Flame | o |
23.1 | 2 | 74 | > 300 | Flame | o |
23.1 | 1.5 | 73 | > 300 | Flame | o |
23.1 | 1.0 | 71 | > 300 | Flame | o |
23.1 | 1.0 | 72 | > 300 | Flame | o |
23.1 | 1.0 | 71 | > 300 | Flame | o |
t1: time to any reaction, e.g.
whistle or flame
t2: time to main reaction, e.g. rupture of tube or flashing
o: tube unchanged
No explosion was observed. The limiting
diameter was less than 1 mm. Therefore, the results had to be evaluated
as negative according to UN tests 1(b) and 2(b): negative "-".
Time / pressure test
Table below shows the used amounts of sample and the results
from the Time / pressure test.
Test 1 | Test 2 | Test 3 | |
Amount in g | 5.0 | 5.0 | 5.0 |
Time to 690 kPag in s | 2.01 | - | - |
Time to 2070 kPag in s | - | - | - |
Pressure rise time in s | - | - | - |
None of the three tests reached a pressure of 2070 kPa. Therefore, the result had to be evaluated as negative according to UN tests 1(c) and 2(c): negative "-". These evaluations indicate no (or slow) deflagration according to the UN tests 1(c) and 2(c).
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Remarks:
- Due to a decomposition energy <800 J/g and due to the fact that the test item consisted mainly of organic components a series 1 type (a) test (propagation of a detonation) was not necessary (see appendix 6 of UN Manual of Tests and Criteria, revision 7 (2019)). Also due to negative results presented above from the UN tests 1(b) (effect of heating under confinement) and 1(c) (effect of ignition under confinement), the test item can be excluded from classification in class 1 (explosives) according to series 1 of the UN Manual of Tests and Criteria, revision 7 (2019).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.