2,4-bis[N'-(4-methylphenyl)ureido]toluene

Flash point

Administrative data

Endpoint:

flash point of flammable liquids

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

appearance / physical state / colour

Type of information:

other: not specified

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

no guideline followed

Principles of method if other than guideline:

The description of appearance was taken from the SDS.

GLP compliance:

no

Physical state at 20°C and 1013 hPa:

solid

Form:

powder

Colour:

light yellow

Odour:

odourless

Substance type:

organic

Conclusions:

The substance KY-MA is a light yellow powder under ambient conditions. The substance has no characteristic odour.

Cross-reference 2

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

October 21, 1992

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

1989

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Decomposition:

yes

Decomp. temp.:

>= 180 °C

Remarks on result:

other: The substance has no melting point.

Preliminary test

Two endothermic peaks, which partly overlap each other, were observed between about 180 and 330°C. At higher temperatures, around about 360°C possibly a small exothermic effect was detected. During the experiment the sample lost 7.99 mg (95%) of its mass and changed into a black powder.

Main study

- First run: this run was performed to investigate the run registered during the preliminary test. The endothermic effect started at about 190°C. The sample lost 4.95 mg (56%) of its mass during this run; it was changed into a yellow/brown powder.

- Second run: during this run, the endothermic effect which was observed in the 1st run could not be detected, which implies that it was caused by an irreversible process, e.g. evaporation, reaction and/or decomposition of (part of) the test substance. The second endothermic effect started at about 247°C. After this run, the sample appeared to be a dark brown powder; it had lost 3.50 mg (40%) of its mass.

- Third run: no endothermic heat effect was observed.; therefore also the second observed endothermic peak is considered to be caused by an irreversible process, e.g. evaporation, reaction and/or decomposition of (part of) the test substance. Between about 275 and 357°C a base-line shift was observed. It is not clear what process caused this shift. The sample lost 0.02 mg (0.2%) of its mass; the residue was a black powder.

Conclusions:

The substance has no melting point up 180°C. At temperatures above 180°C the substance evaporates, reacts and/or decomposes.

Executive summary:

In accordance with EU Method A.1 (1989) and according to GLP principles the melting point of the substance (a solid under ambient conditions) was determined using DSC. It was found that the substance has no melting point. Evaporation, reaction and/or decomposition of the substance starts at 180°C.