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Registration Dossier
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EC number: 415-110-8 | CAS number: 54417-53-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- (R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride
- EC Number:
- 415-110-8
- EC Name:
- (R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride
- Cas Number:
- 54417-53-7
- Molecular formula:
- C20H25NO4.HCl
- IUPAC Name:
- (1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
- Test material form:
- solid: crystalline
Constituent 1
Study design
- Inoculum or test system:
- not specified
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 2
- Sampling time:
- 28 d
- Details on results:
- 7 % degradation after 4 d
1 % degradation after 14 d
7 % degradation after 21 d
2 % degradation after 28 d
BOD5 / COD results
- Results with reference substance:
- 67 % degradation after 4 d
80 % degradation after 14 d
90 % degradation after 21 d
94 % degradation after 28 d
Applicant's summary and conclusion
- Interpretation of results:
- not readily biodegradable
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