(S)-3-(tert-butylamino)propane-1,2-diol

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

(Q)SAR

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Reference

Title:

ECOSAR (US EPA)

Year:

2017

Bibliographic source:

ECOSAR (US EPA) Version 2.0

Materials and methods

Principles of method if other than guideline:

- Software tool(s) used including version: ECOSAR (US EPA)
- Model(s) used: ECOSAR (US EPA) Version 2.0
- Model description: see field 'Attached justification'

GLP compliance:

no

Test material

Test material information

1

Reference substance name:

(S)-3-(tert-butylamino)propane-1,2-diol

EC Number:

250-125-1

EC Name:

(S)-3-(tert-butylamino)propane-1,2-diol

Cas Number:

30315-46-9

Molecular formula:

C7H17NO2

IUPAC Name:

3-(tert-butylamino)propane-1,2-diol

Test material form:

solid: particulate/powder

Results and discussion

Effect concentrations

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

99.65 mg/L

Nominal / measured:

estimated

Remarks on result:

other: QSAR prediction

Applicant's summary and conclusion

Conclusions:

(2S)-3-(tert-butylamino)propane-1,2-diol is a organic chemical that is likely to be within the domain of ECOSAR domain.
Aliphatic Amines SAR: Daphnid 48-hr LC50 = 99.65 mg/L

The predictions do not indicate extreme or acute toxicities relevant for classification and labelling. The assessment indicates that the prediction is suitable for the regulatory conclusion.