Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Effects on fertility

Description of key information

The substance was not toxic to the fertility.

Link to relevant study records
fertility, other
Type of information:
experimental study
Adequacy of study:
other information
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Route of administration:
Type of inhalation exposure (if applicable):
not specified
not specified
Duration of treatment / exposure:
90 days exposure
Dose / conc.:
400 mg/m³ air

No adverse, substance-related effects on the reproductive organs were observed. Changes in individual hormone parameters and increased epididymal sperm counts were evaluated by the authors as unclear or as not assignable due to the high variability of the data and the relatively low number of animals/group and sex.

Under the test conditions, no adverse substance-related effects on the reproductive organs were observed.

Effects on developmental toxicity

Description of key information

No data available.

Justification for classification or non-classification

Data available are deemed to be inconclusive to assess the classification in accordance with CLP Regulation.

Additional information