Registration Dossier
Registration Dossier
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EC number: 844-232-8 | CAS number: 102731-54-4
Endpoint summary
Administrative data
Description of key information
Aquatic studies evaluating the toxicity of the substance to aquatic organisms are available for two different trophic levels. All studies were performed according to international guidelines and GLP.
Short-term toxicity to fish
The acute toxicity of the test item to fish was estimated using ECOSAR v1.11 (EPI Suite v4.11).
The predicted 96-hour LC50 fish acute value was 4.522 mg/L.
Short-term toxicity to invertebrates
The acute toxicity of the test item on Daphnia magna was determined in a 48-hour semi-static test with a test medium renewal after 24 hours according to the OECD Guideline for Testing of Chemicals, No. 202 (2004) and the Commission Regulation (EC) No. 440/2008, Part C.2. The 48-hour EC50 was calculated to be 10 mg/L with 95 % confidence limits of 9.0 and 12 mg/L.
Toxicity to algae
The impact of the test item on the growth of the freshwater green algal species Pseudokirchneriella subcapitata was investigated in a 72-hour static test according to the OECD Guideline 201 (2006, corrected 2011) and the Commission Regulation (EU) No. 2016/266, C3.
Due to the almost complete decrease of the test item after 72 hours and since the biomass in the control already increased by a factor of 19.5 over the first 48 hours it was decided, to calculate the mean measured concentrations as the geometric mean of the concentrations measured at the sampling dates after 0, 24 and 48 hours. It was also decided to reflect the biological 48-hour endpoints based on these mean measured concentrations.
Therefore, the 48-h ErC50 for growth rate was calculated to be 3.7 mg/L with 95 % confidence limits of 9.0 and 12 mg/L. The 48-h ErC10 for growth rate was determined to be 0.12 mg/L (95 %-CL: 0.077 - 0.17).
Toxicity to microorganisms
In a ready biodegradability test no toxic effects to microorganisms were observed after incubation with 42.2 mg/L test substance.
Additional information
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