Registration Dossier
Registration Dossier
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EC number: 618-233-7 | CAS number: 890707-28-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 November 2019 to 16 December 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- OECD Guideline No. 117 (2004)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Identification: 2-AMINO-5-CHLORO-N,3-DIMETHYLBENZAMIDE
Batch: 628-042-00
CAS number: [890707-28-5]
Purity: 99.0 %
Analysis date: 16 October 2019
Expiry date: 16 October 2021
Supplier: ADAMA Makhteshim Ltd.
Appearance: Beige powder
Packaging: White opaque plastic bag
Quantity: received 1 kg
Date of receipt: 12 November 2019
Storage: In darkness at room temperature
gIdentification number: 19-193 - Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.7
- Temp.:
- 25 °C
- Remarks on result:
- other: pH value was not measured, diluent is between pH 6 and 7 and transferable to complete solution
- Conclusions:
- By HPLC method the octanol/water partition coefficient of 2-Amino-5-chloro-N,3-dimethylbenzamide is equal to 1.7.
- Executive summary:
By HPLC method accoding to regulation (EC) No. 2016/266 - EC A.24. method (2016) and OECD Guideline No. 117 (2004) the partisition coefficient for 2-Amino-5-chloro-N,3-dimethylbenzamide was determined to be equal to 1.7.
Reference
Description of key information
For 2-Amino-5-chloro-N,3-dimethylbenzamide by application of (EC) No. 2016/266 - EC A.24. method (2016) and using the HPLC test method OECD Guideline No. 117 (2004), it was shown that the the octanol/water partition coefficient of is equal to 1.7.
The partition coefficient is in good agreement with screening tests of solubility in organc solvents.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.7
- at the temperature of:
- 25 °C
Additional information
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