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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2006
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006
Report date:
2006

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-({(5S)-2-Oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dione
EC Number:
610-201-0
Cas Number:
446292-08-6
Molecular formula:
C22 H19 N3 O6
IUPAC Name:
2-({(5S)-2-Oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dione

Results and discussion

Water solubilityopen allclose all
Key result
Water solubility:
0.012 - 0.012 g/L
Temp.:
20 °C
pH:
6.6
Remarks on result:
other: Mean value (column 1) = 1.21E-02 g/L
Water solubility:
0.012 - 0.012 g/L
Temp.:
20 °C
pH:
6.5 - 6.6
Remarks on result:
other: Mean value (column 2) = 1.20E-02 g/L
Details on results:
Result oft he preliminary test: 9.0 E-03 g/L

Applicant's summary and conclusion

Conclusions:
Oxaphthalimid has a water solubility of 1.2E-02 g/L.