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EC number: 209-162-9 | CAS number: 557-21-1
There was no clinical signs and mortalities related to the application of test substance during this study. There was no significant body weight changes related to the application of test substance during this study. In the case of vehicle control group, the skin reaction (edema or erythema) was not observed at 24, 48 hours after removal of challenge patch. Therefore, the final sensitisation rate of vehicle control group was 0 % and vehicle control was classified with “Weak”(Grade I) sensitizer. In the case of test substance treated group, the skin reaction (edema or erythema) was not observed at 24, 48 hours after removal of challenge patch. Therefore, the final sensitisation rate of test substance treated group was 0 % and the test substance was classified with “Weak”(Grade I) sensitizer.
For that endpoint, one reliable study to assess skin sensitisation in vivo on the registered substance on female guinea pig was available. The study was performed according to the OECD Guideline 406 (Skin Sensitisation).
Under the experimental conditions, the sensitisation rate of Zinc cyanide batch n°10185145 was considered as 0 % and Zinc cyanide batch n°10185145 was classified with “Weak”(Grade I) sensitizer according to “criteria for skin sensitisation” in female Hartley Guinea Pigthe.
The validity criteria were successful and the study was therefore regarded as acceptable for that endpoint.
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