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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
May 11 - 15, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
not specified
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
(2-fluoro-3-methoxyphenyl)boronic acid
EC Number:
609-099-0
Cas Number:
352303-67-4
Molecular formula:
FC6H3(OCH3)B(OH)2
IUPAC Name:
(2-fluoro-3-methoxyphenyl)boronic acid
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
Purity: 100.2%
Batch No.: 18051400
Expiration date: March 14, 2019
Physical status: Off-white solid

Results and discussion

Water solubility
Key result
Water solubility:
3.62 g/L
Conc. based on:
test mat. (dissolved fraction)
Loading of aqueous phase:
5 other: uL
Incubation duration:
> 24 h
Temp.:
20 °C
pH:
6.5
Remarks on result:
other: RSD% = 0.60% (n=3)
Details on results:
The mean result of water solubility of FMPBA was 3.62 g/L at 20 C, the RSD% was 0.60% (n=3)

Applicant's summary and conclusion

Conclusions:
The water solubility of FMPBA was determined compatible wit hthe Principles of OECD Guidelines for testing of Chemicals No. 105 'Water Solubility'. Based on the test results, the water solubility of FMPBA at 20 C was 3.62 g/L, RSD% was 0.60 (n=3).