Registration Dossier
Registration Dossier
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EC number: 443-800-9 | CAS number: 40031-31-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003-01-27
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- OECD guidelines for testing of chemicals no.107: “Partition coefficient (n-octanol/water): Shake
Flask Method”, Adopted July 27, 1995. - Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Version / remarks:
- EEC directive 92/69 EEC, Part A, Methods for the determination of physico-chemical properties,
A.8: “Partition coefficient”, EEC Publication no. L383, December 1992. - Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- NA
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- -2.16
- Temp.:
- 20 °C
- pH:
- 3.1
- Key result
- Type:
- Pow
- Partition coefficient:
- 0.007
- Temp.:
- 20 °C
- pH:
- 3.1
- Details on results:
- NA
- Conclusions:
- The partition coefficient (n-octanol/water) of (S)-1,3,4-trihydroxybutan-2-one was determined to be 7x10-3 (log P0= -2.16) at 20.0 ± 1.0°C using the Flask-shaking method.
- Executive summary:
The partition coefficient (n-octanol/water) of (S)-1,3,4-trihydroxybutan-2-one was determined to be 7x10-3 (log P0= -2.16) at 20.0 ± 1.0°C using the Flask-shaking method.
Reference
No remarks
Description of key information
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -2.16
- at the temperature of:
- 20 °C
Additional information
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