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EC number: 821-932-1
CAS number: 694510-10-6
objective of the present study was to identify potential toxic effects
of the test item after single oral administration to rats in a stepwise
The study was started with 2000 mg/kg in 3
female rats and continued with further 3 females treated with 2000 mg/kg.
and clinical signs were monitored for at least 6 hours after
administration and then daily. All animals were weighed before treatment
(day 1) and on days 2, 4, 6, 8, 11, 13, and 15. At the end of the
observation period, all surviving rats were sacrificed and subjected to
a detailed necropsy.
No mortality occurred during the
course of this study.
No clinical signs of toxicity were
The body weight development was
inconspicuous throughout the study.
The gross pathological examination
revealed no organ alterations.
test item has no acute toxic potential under the conditions of the
present study, and the LD50value is higher than 2000 mg/kg
after single oral administration in female rats.
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