Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 261-598-9 | CAS number: 59089-67-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
- Eye contact
Wash immediately with large amounts of water or normal saline. Keep eyelids open with the finger. Get medical advice ad show him the label.
- Skin contact
Remove contaminated clothes and shoes immediately. Wash affected area with soap or mild detergent and large amount of water until no evidence of substance remains (15-20 minutes). Get medical advice ad show him the label.
- Ingestion
If swallowed wash mouth with water provided person is conscious. Get medical advice ad show him the label.
- Inhalation A
void breathing dusts that may be generated by handling of the product. Remove the person from the exposed area to fresh air immediately. Get medical advice in case of significant exposure.
Fire-fighting measures
- Suitable extinguishing media: Nebulised water, chemical powder, foam , CO2.
- Hazardous combustion products: May produce toxic fumes of Cox, HF.
Don’t try to extinguish the fire without an autonomous respiratory device (SCBA) and protective adapted clothes.
Wear boots, overalls, gloves, eye and face protection and breathing apparatus. Equipment must be conformed with EN criteria and used in highest condition of protection on the basis of the information reported in the previous sub-sections.
Accidental release measures
For non-emergency personnel
- Eye Wear suitable protected devices.
- Skin Wear suitable clothes with full body protection.
- Inhalation In case of fire and/or explosions avoid to breathe smokes and vapors. Use a respiratory device autonomous (SCBA) and adapted protective clothes. The vapors can be eliminated through nebulised with water.
In case of accidental release in the environment avoid that the substance can reach drains, surface water and ground water.
Collect all of the material scattered on the ground with protective equipment adapted and put it in a clean and dry container.
Recover the substance for suction or with other mechanic means and wash the with plenty of water and cleanings. Store the recovered product recovered in wait of the skilled disposal society. If the effusion happened in highway or in a public place, suitable trickiness should be adopted in order to protect the people from any risk
Handling and storage
The substance is an intermediate for the production of active pharmaceutical ingredients: adopt technical, control and procedural measures, such as to minimize exposure to workers and the environment during use, according to the provisions of Art. 17/18 of the REACH Regulation
Handle away from sparkles and flames - sources of ignition
Handle in a well ventilated place
Avoid contact with incompatible materials
Wear suitable Personal Protection Equipment (see section 8)
Keep the substance away from drains, surface or ground waters
Do not eat, drink and smoke in the working areas
Wash hands after handling the substance
Remove contaminated clothing and protective equipment before entering eating areas
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
Adopt technical containment and process control measures to minimize worker exposure. Strictly confine the substance by technical devices during all processing phases (purification, cleaning, equipment maintenance, sampling, analysis, loading and unloading, disposal and storage). Appropriate technical measures include: the use of closed systems and adequate ventilation.
Use suitable Personal Protective Equipment .
Stability and reactivity
The substance is stable at the normal condition of temperature and pressure and if stored in closed containers in well ventilated and cool place
Disposal considerations
Refers to Community/National/Local requirements concerning the waste disposal.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.