Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Cross-reference
Reason / purpose:
data waiving: supporting information
Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions
Reason / purpose:
reference to same study
Reason / purpose:
reference to same study
Reason / purpose:
reference to same study
Qualifier:
no guideline followed
Principles of method if other than guideline:
Saturated solutions of TMPTS in water were prepared; then the TMPTS in the solutions was quantitatively analyzed with UPLC.
GLP compliance:
no
Type of method:
other: UPLC was used for measuring water solubility
Water solubility:
3.6 µg/L
Conc. based on:
test mat.
Remarks on result:
other: no further information available, but standard conditions / room temperature assumed
Conclusions:
water solubility = 3.6 µg/L (insoluble; <0.1 mg/L)
The study (no GLP) was performed in accordance with national standard methods with acceptable restrictions on the substance to be registered itself, the test procedure is well documented and therefore reliability of Klimisch 2 has been assigned.
Executive summary:

The liquid chromatography was used for measuring water solubility in a non GLP study. Using the UPLC method, The water solubility of the test item was determined to be 3.6 µg/L at room temperature.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion