Registration Dossier

Administrative data

Endpoint:
skin sensitisation: in vitro
Type of information:
other: expert assessment
Adequacy of study:
key study
Study period:
2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Assessment based on the properties of the indvidiual constituents of the substance

Data source

Reference
Reference Type:
other: expert assessment
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
An assessment was conducted based on the properties of the indvidiual constituents of the substance.
GLP compliance:
no
Type of study:
other: Assessment based on the properties of the indvidiual constituents of the substance

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Results and discussion

In vitro / in chemico

Results
Remarks on result:
other: An assessment was conducted based on the properties of the indvidiual constituents of the substance. It concluded that Phenol, ethoxylated does not meet the criteria for classification as sensitising to the skin according to the CLP Regulation.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
An assessment was conducted based on the properties of the indvidiual constituents of the substance. It concluded that Phenol, ethoxylated does not meet the criteria for classification as sensitising to the skin according to the CLP Regulation.
Executive summary:

The capacity of Phenol, ethoxylated to induce skin sensitisation was assessed based on the available information on its constituents.

2-phenoxyethanol and 2-(2-phenoxyethoxy)ethanol are not classified as sensitising to the skin based on available experimental data.

Considering the structural similarities between the constituents of Phenol, ethoxylated and in the absence of experimental data on the substance, 2-[2-(2-phenoxyethoxy)ethoxy]ethanol is not expected to induce skin sensitisation.

It is concluded that Phenol, ethoxylated does not meet the criteria for classification as sensitising to the skin according to the CLP Regulation.