Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
other: expert assessment
Adequacy of study:
key study
Study period:
2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Assessment based on the properties of the indvidiual constituents of the substance

Data source

Reference
Reference Type:
other: expert assessment
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
An assessment was conducted based on the properties of the indvidiual constituents of the substance.
GLP compliance:
no
Test type:
other: Assessment based on the properties of the indvidiual constituents of the substance
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Results and discussion

Effect levels
Remarks on result:
other: An assessment was conducted based on the properties of the indvidiual constituents of the substance. It concluded that Phenol, ethoxylated should be classified as Acute Tox 4; H302.

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria
Conclusions:
An assessment was conducted based on the properties of the indvidiual constituents of the substance. It concluded that Phenol, ethoxylated should be classified as Acute Tox 4; H302.
Executive summary:

The Acute Oral Toxicity of Phenol, ethoxylated was assessed based on the available information on its constituents.

2-phenoxyethanol is associated to a Harmonised Classification as Acute Tox 4; H302, which was confirmed during the REACH Registration of the substance.

2-(2-phenoxyethoxy)ethanol was concluded not to meet the criteria for classification for this endpoint based on available experimental data on the substance.

Considering the structural similarities between the constituents of Phenol, ethoxylated, and in the absence of experimental data on the substance, 2-[2-(2-phenoxyethoxy)ethoxy]ethanol is not expected to be toxic following an acute exposure via the oral route.

While it can be concluded according to the CLP Regulation that Phenol, ethoxylated does not meet the criteria for classification as toxic following an acute oral exposure, it is suggested to classify the substance as Acute Tox 4; H302 to compensate the lack of information on one of the constituents of the substance.