Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 404-240-0
CAS number: 95962-14-4
NECTALACTONE; NECTARYL; NECTARYL-LRG 1371
The mutagenic potential of the test substance was tested in the
mouse using the micronucleus test OECD Guideline No. 474. The test
substance was administered by the oral route at the dose level of
4800mg/kg as described in the preliminary study.
A negative control (administration of vehicle) and a positive
control (administration of a standard mutagenic substance) were included
in this study.
The animals (5 males and 5 females per group) were killed 24, 48 or 72
hours after the administration of the test substance. For each animal an
examination of 1000 polychromatophile erythrocytes obtained from the
femoral bone marrow was performed. The frequency of micronuclei was
calculated for each animal and for each group.
Under the experimental conditions employed,the test substance NECTARYL
did not induce mutagenic effects in the mouse.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again