Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
not specified
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
GLP compliance:
yes
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction products of 2,3-epoxypropyl phenyl ether and 2,2'-iminodi(ethylamine)
EC Number:
948-518-4
Molecular formula:
(C13H23N3O2 . C31H43N3O6)x
IUPAC Name:
Reaction products of 2,3-epoxypropyl phenyl ether and 2,2'-iminodi(ethylamine)
Test material form:
liquid
Details on test material:
PGE-DETA adduct

Results and discussion

Water solubilityopen allclose all
Water solubility:
101 vol%
Conc. based on:
test mat. (dissolved fraction)
Loading of aqueous phase:
0.103 g/L
Temp.:
20 °C
pH:
10.2
Water solubility:
89.4 vol%
Conc. based on:
test mat. (dissolved fraction)
Loading of aqueous phase:
0.893 g/L
Temp.:
20 °C
pH:
10.9
Water solubility:
69.8 vol%
Conc. based on:
test mat. (dissolved fraction)
Loading of aqueous phase:
7 g/L
Temp.:
20 °C
pH:
11.4

Applicant's summary and conclusion

Conclusions:
The water solubility of the test item at 20.0 ± 0.5 °C has been determined to be loading rate dependent and generated the following result at 10 g/L: concentration 7.0 g/L - Loading rate 69.8%:
Executive summary:

Water Solubility. The water solubility of the test item at 20.0 ± 0.5 °C was demonstrated to be loading rate dependent, using the flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.