Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999
Report date:
1999

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
Deviations:
no
Principles of method if other than guideline:
No other methods
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
(1S,2S,6R)-3,5-dibenzyl-4-oxo-8lambda4-thia-3,5-diazatricyclo[6.3.0.0^{2,6}]undecan-8-ylium bromide
EC Number:
700-349-5
Cas Number:
33719-11-8
Molecular formula:
C22H25BrN2OS
IUPAC Name:
(1S,2S,6R)-3,5-dibenzyl-4-oxo-8lambda4-thia-3,5-diazatricyclo[6.3.0.0^{2,6}]undecan-8-ylium bromide

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
0.625 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
DOC removal

Results and discussion

% Degradation
Parameter:
% degradation (DOC removal)
Value:
22
Sampling time:
28 d
Details on results:
Degradation of positive control aniline was found to be >98% after 28 days.

Any other information on results incl. tables

No overall remarks

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Interpretation of results:
inherently biodegradable
Conclusions:
Biodegradation < 10 % after 10 days (interpolated).
Executive summary:

The biodegradation of thiophanium bromide is <10 % after 10 days (interpolated). The compound is not readily biodegradable under the conditions of the test.