Registration Dossier
Registration Dossier
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EC number: 827-277-8 | CAS number: 1771689-37-2
Endpoint summary
Administrative data
Description of key information
Short-term, toxicity to fish
Key, fish acute toxicity, Danio rerio, limit test, OECD 203, semi-static, GLP: LC50 (96h) > 100 mg/L nominal
Short-term toxicity to aquatic invertebrates
Key, acute immobilisation, Daphnia magna, limit test, OECD 202, semi-static, GLP: EC50 (48h) > 0.88 µg/L geometric mean measured, EC50 (48h) > 100 mg/L nominal
Toxicity to aquatic algae and cyanobacteria
Key, growth rate inhibition, Raphidocelis subcapitata (formerly known as Pseudokirchneriella subcapitata), limit test, OECD 201, GLP: ECr50 (72h) > 13.0 µg/L geometric mean measured and > 100 mg/L nominal, ECr10 (72h) > 13.0 µg/L geometric mean measured and > 100 mg/L nominal
Toxicity to microorganisms
Key, OECD 209, GLP, static, results: EC10(3h) 53.4 mg/L (nominal) and EC50 (3h) > 1000 mg/L (nominal)
Additional information
No acute toxicity is recorded at levels up to the water solubility. But taking in account the very low solubility (below 2 μg/L at 20 °C) of the test item and the very poor biodegradation (0.4 % at 28d) as well as the potential to bioaccumulate (log Kow 9.674), the substance should be classified as H413 “May cause long lasting harmful effects to aquatic life” (Category Chronic 4) in accordance with Regulation (EC) No 1272/2008, unless other data exists showing classification to be unnecessary.
This "safety net" classification includes poorly soluble substances for which no acute toxicity is recorded at levels up to the water solubility, and which are not rapidly degradable and have an experimentally determined BCF ≥ 500 (or, if absent, a log K ow ≥ 4), indicating a potential to bioaccumulate. This classification is also recommended in OECD Guidance Document No. 27 based on the outlined criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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